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The recent detections of a large number of candidate active galactic nuclei at high redshift (i.e.  $z\gtrsim 4$) has increased speculation that heavy seed massive black hole formation may be a required pathway. Here we re-implement the so-called Lyman-Werner (LW) channel model of Dijkstra et al. (2014) to calculate the expected number density of massive black holes formed through this channel. We further enhance this model by extracting information relevant to the model from the $\text{𝚁𝚎𝚗𝚊𝚒𝚜𝚜𝚊𝚗𝚌𝚎}$simulation suite. $\text{𝚁𝚎𝚗𝚊𝚒𝚜𝚜𝚊𝚗𝚌𝚎}$is a high-resolution suite of simulations ideally positioned to probe the high- $z$universe. Finally, we compare the LW-only channel against other models in the literature. We find that the LW-only channel results in a peak number density of massive black holes of approximately at $z\sim 10$. Given the growth requirements and the duty cycle of active galactic nuclei, this means that the LW-only is likely incompatible with recent JWST measurements and can, at most, be responsible for only a small subset of high- $z$active galactic nuclei. Other models from the literature (e.g. rapid assembly; relative velocities between baryons and dark matter) seem therefore better positioned, at present, to explain the high frequency of massive black holes at high $z$. 

Abstract The Laser Interferometer Space Antenna (LISA) will be a transformative experiment for gravitational wave astronomy, and, as such, it will offer unique opportunities to address many key astrophysical questions in a completely novel way. The synergy with ground-based and space-born instruments in the electromagnetic domain, by enabling multi-messenger observations, will add further to the discovery potential of LISA. The next decade is crucial to prepare the astrophysical community for LISA’s first observations. This review outlines the extensive landscape of astrophysical theory, numerical simulations, and astronomical observations that are instrumental for modeling and interpreting the upcoming LISA datastream. To this aim, the current knowledge in three main source classes for LISA is reviewed; ultra-compact stellar-mass binaries, massive black hole binaries, and extreme or interme-diate mass ratio inspirals. The relevant astrophysical processes and the established modeling techniques are summarized. Likewise, open issues and gaps in our understanding of these sources are highlighted, along with an indication of how LISA could help making progress in the different areas. New research avenues that LISA itself, or its joint exploitation with upcoming studies in the electromagnetic domain, will enable, are also illustrated. Improvements in modeling and analysis approaches, such as the combination of numerical simulations and modern data science techniques, are discussed. This review is intended to be a starting point for using LISA as a new discovery tool for understanding our Universe.